[Objective] This paper aims to demonstrate the spatial autocorrelation and the pattern of soil pH value in order to find the main influencing environmental factors.[Methods] Classical statistics and 3S technology were used.[Results] The spatial distribution of soil pH value in different soil depth showed a highly positive spatial autocorrelation and had obvious spatial clusters, nearly no isolated distribution was found. The factors influencing the spatial distribution of soil pH value in different soil depth ranked as:vegetation coverage, rocky desertification and geological background.[Conclusion] The spatial heterogeneity of soil pH value was affected by the content of acid materials under different vegetation covers, and the influence of rocky desertification and geological background on soil pH value is a comprehensive reflection of typical karst environment.