Abstract: [Objective] Widely-distributed saline soils in coastal reclamation zones of China are of great significant obstacle for hindering regional agricultural productivity promotion and sustainable agricultural development. This study analyzed soil physicochemical properties, salt ion content, and maize growth in response to adding different levels of biochar, desulfurized gypsum, and chicken manure coupled with conventional fertilization in coastal saline soils. [Methods] A field-controlled experiment was conducted in the Dafeng coastal reclamation areas of Yancheng, coupled with maize (Liyu 88) cultivation as the aboveground crop. The experiment comprised ten treatments: control (conventional fertilization, CK); compound fertilizer combined with low (1), medium (2), and high (3) levels of biochar (BC1~BC3), desulfurized gypsum (DG1~DG3), and chicken manure (CM1~CM3). [Results] (1) All amendments improved soil physicochemical properties, salt ion contents, and their composition to some extent. However, the addition of desulfurized gypsum exhibited an excellent effect in improving the core physicochemical indicators of coastal saline soils, particularly in reducing in soil pH and electrical conductivity (EC). Furthermore, the medium level of desulfurized gypsum (DG2) significantly promoted soil salt ions reduction, in particular for declining Na? and Cl? content and the SAR (sodium adsorption ratio). In addition, this treatment also promoted the accumulation of K?, Ca2?, Mg2?, and SO?2?, but had little effect on NO??. (2) The promoting effect of desulfurized gypsum addition on maize growth was superior to that of biochar and chicken manure. Notably, under the medium level of desulfurized gypsum (DG2) treatment, maize yield was the highest over all treatments in the experimental period, reaching 2.337 t/hm2 and 2.190 t/hm2, respectively. [Conclusion] In this study, in terms of saline soil quality promotion, the medium-level addition of desulfurization gypsum (5 t/hm2) (DG2) demonstrated a relatively good improvement effect in soil desalination and meanwhile increasing maize yield in coastal saline soils, which can be considered in the future.