[Objective] The regional priority with regard to soil and water loss and ecological restoration was explored to provide some major decision-making bases for ecological environment management and social and economic development in Longmen Mountains area.[Methods] Based on the powerful spatial analysis function of GIS, the spatial values of soil erosive sensitivity in Longmen Mountains area were identified and calculated in consideration of all comprehensive influence factors of soil and water loss, as precipitation, soil erosion, topography relief and vegetation cover, etc. According to the classification method of natural breakpoint of ArcGIS, areas in term of sensitivity degree of soil erosion were designated as following:insensitive area, sensitive area, low sensitive area, moderate sensitive area and extreme sensitive area.[Results] The highest sensitivity areas were mainly distributed in the eastern piedmont hills and alluvial plains, accounting for 34.12% of the total area. Moderate sensitivity areas were mainly distributed in the central hilly areas, accounting for 28.30% of the total area. Low sensitivity zone were mainly distributed in the western mountains, accounting for 13.65% of the total area. The covered areas by different sensitivity degree were largely overlapped spatial distribution of human activity frequency.[Conclusion] The sensitivity of soil and water loss in the study area had obvious regional differentiation with regard to the erosive sensitivity. It is the frequent human activity that cause strong disturbance to natural ecosystem and cause subsequent strong sensitivity to soil erosion.