[Objective] Quantitative reconstruction of the 100-year resolution precipitation sequence of the Qinghai-Tibet Plateau since Holocene provides basic data for the environmental evolution of the Qinghai-Tibet Plateau and its prediction of future climate scenarios.[Methods] Using the high-resolution spore-pollen data from the Ruergai Basin and Tarongcuo Lake on the Qinghai-Tibetan plateau, we reconstructed precipitation changes in the eastern and western plateau since the Holocene by weighted average partial least squares regression(WAPLS) and modern analogue(MAT).[Results] ① The precipitation variation on the plateau was obviously divided into three stages. The precipitation in the early Holocene(10.5~8.9 kaBP) tended to fluctuate, and the average precipitation was slightly higher than that of the modern. The middle Holocene(8.9~3.2 kaBP) was a period of abundant precipitation and the extreme time in the eastern and western regions reached 6.7 kaBP and 7.4 kaBP, respectively, and the precipitation was higher than the modern 42.4 mm and 200 mm respectively. In the later Holocene(after 3.2 kaBP), the precipitation in the east continued to decrease, which was about 70 mm lower than the previous period, while the precipitation in the west increased, similar to the modern level; ② Precipitation extreme events:the extreme drought events on the plateau were relatively consistent and occurred around 1.8, 3.4, 6.2 and 9.5 kaBP.[Conclusion] In the early and middle Holocene, the precipitation was generally higher than that in the modern times. At the end of the Holocene, the precipitation in the east and west had a downward trend, and the precipitation in the west increased around 1.2 kaBP. Reconstruction sequences are comparable to the other records with a high or low resolution, which means reconstruction sequences are representative and relatively accurate.