[Objective] The multi-functionality of land use and its obstacles in Wuhan City during 2005-2017 was evaluated in terms of economy, society and ecology in order to improve the efficiency of land use and promote the rational regional land use and achieve regional sustainable development.[Methods] According to the target layer, index layer and element layer framework, an evaluation index system was constructed, and the entropy weight TOPSIS method was used to determine the index weight and calculate the obstacle degree.[Results] ① During the study period, the comprehensive function of land use in Wuhan City showed an overall upward trend, the coordination of functions showed a Z-shaped decline, the dominance of functional changes showed a wavy decline, and land use became increasingly diversified. ② The economic, social and ecological functions had different growth levels. Among them, the economic and social functions experienced low-intermediate-good-quality development stages, and the overall growth was rapid; the ecological functions experienced low-intermediate-quality development. At this stage, although there were small fluctuations, the overall growth was substantial. ③ The degree of economic and social dysfunction declined, while dysfunction of ecological functions continued to rise.[Conclusion] Wuhan City should pay attention to the improvement of ecological functions, transform the economic development mode, promote industrial upgrading, implement cleaner production, reduce the pollution of the three wastes, and pay attention to the protection of water resources and realize the sustainable use of land.