As a case study in Gansu province, the damp index, days on strong wind, soil texture and vegetation cover in winter and spring in Gansu province on sensitivity to land desertification and their spatial heterogeneity are assessed based on GIS. The result indicates that high sensitive region in Hexi area, middle and light sensitive region in Longzhong and Longdong loess plateau, Qilian mountainous region, Longnan mountainous region and Gannan plateau are light sensitive or non sensitive area.