Yanchi County is one of the most serious counties among the Ningxia Hui Autonomous Region, which desertification area is believed to occupy 39.4% of the total desertification area in Ningxia.This paper utilized Geographic Information System of the key windy-sandy region and based on the monitoring data of 1994 and 1999, to analyze the dynamic change of desertification and landuse, and study the relation between them. It also put forwards some advices for the Ningxia Hui Autonomous Region, to combat desertification in the future.