Abstrcat The geographic distribution, soil forming conditions, physico-chemical properties and main subgroups of desertified soil in Hexi Corridor are discussed. Effect of the desertified soil and fertilization in the gray-brown desert soil is also studied. After three years cultivation of Ephedra intermedia whose fresh grass yield is 12.17 t/hm~2. Compared to CK in 0-20 cm soil layer, the soil water content, granular structure(0.25 mm) and the total porosity are increased by 64.2 g/kg, 14.31% and 11.32% separately. The apparent density is decreased by 0.30 g/cm, soil pH from 8.32 to 7.99 and total salt by 1.72 g/kg. The rate of desalination reaches to 49.85%. At the same time, the content of soil organic matter, rapidly available N, rapidly available P and rapidly available K increase too