The feasibility of information extraction for the degradation of salinized soil by means of RS in the Yellow River delta region was obtained through analyzing the spectral characteristics of TM & ETM data from the Landsat series satellites and constructing the saline information model. The results showed a deteriorating tendency of severe soil salinization in the past 10 years, and the trend in 2007 compared to 2003 was more severe than that in 2011 compared to 2007. However, the increasing trend slowed down in 2011, but it was still heavier than that in 2003. The degradation of salinized soil was obvious, that meant soil salinization becoming more serious. All the land degradation was closely related to human activities, including ignoring the constant protection and rational utilization of land in Gudong oilfield construction, the construction of coastal areas baysalt brine and aquaculture ponds, mild salinization area increased and the excavation of artificial irrigation area, the introduction of the Yellow River runoff and water conservancy engineering measures. The influence of human activities on soil salinization has side effects of both positive and negative.