[Objective] The distribution pattern of sand-driven wind regimes, drift potentials, sand flux and particle size along the desert oasis transitional zone in the Dunhuang oasis adjacent to Mingsha Mountain was investigate in order to provide a theoretical basis for clarifying the process of aeolian sand in desert and oasis regions. [Methods] Based on the data from the synchronous wind velocity, sand flux and the size of sand grains, the characteristics of aeolian sand environments were calculated along the desert oasis transitional zone. [Results] Because of the differences of the material composition, spatial structure and hydrothermal conditions, wind velocity gradient and cumulative time of sand-driven wind existed significant differences. By the interaction of the desert and oasis, two dominant winds existed desert-oasis transitional zone. From the point of near surface granularity characteristics along the distribution, coarse sand content gradually reduced and silt and clay content increased relatively from the desert to the oasis. Desert-oasis transitional zone was the important part of the ecosystem, and had significance in maintaining a stable transition. [Conclusion] For the oasis sand hazard prevention and control, we should give full consideration to the role of regulation and buffering of desert-oasis transitional zone in view of atmospheric circulation.