[Objective] Field experiments were conducted to study effects of different treatments of fertilization and irrigation on rice yield, soil nutrient and enzyme activity under straw amendment, and to provide theoretical support for the development of high quality, highly effective ecoagriculture. [Methods] Through field experiment, we designed three kinds of irrigation patterns and three nitrogen levels, total of nine experimental treatments, and set up three no straw treatments as a control. [Results] The application rate of nitrogen fertilizer was 225 kg/hm², the shallow wetland regulation irrigation mode can help control the tiller, reduce plant height, form a reasonable population structure. Different treatments of fertilization and irrigation had no significant effect on rice per panicle, seed setting rate, shallow wetlands regulation irrigation mode can effectively improve rice panicles and grain weight, thus improving rice yield. The rate of fertilizer was 225 kg/hm², the shallow wetlands regulation irrigation mode can effectively improve the amount of SOM(soil organic matter), TN(tatl N), AP(availale P), AK(available K). Straw amendment can significantly improve soil invertase activity, reduce soil urease activity, while the soil catalase activity had no significant change. In straw amendment field, rate of nitrogen fertilizer was 225 kg/hm², the shallow wetlands regulation irrigation mode improved the most signifycantly on soil invertase activity, but different treatments of fertilization and irrigation did not significantly reduce the soil urease activity. [Conclusion] In straw amendment field, when the rate of fertilizer was 225 kg/hm², shallow wetlands regulation irrigation mode can effectively improve rice yield and soil fertility.