[Objective] The objective of the study is to investigate and analyze the seed plant flora resources in order to provide the support for improvement of the economic income of local residents and the structure of rural industry. [Method] Based on collected data, a comprehensive analysis of the characteristics of the area, the life style and the resources of the seed plants was carried out by cousulting the list of seed plant. [Results] In south margin of Tengger desert, there are 31 species of seed plants, belonging to 16 families, 31 genera and families. The Chenopodiaceae, Compositae, Gramineae and Herbaceous plants accounted for 67.7% of the total species. The ecological species, fodder species and medicinal species accounted for 83.87%, 51.61%% and 58.06% of the total species respectively. [Conclusion] The Chenopodiaceae, Compositae and Gramineae are families with large number of species, and occupied an important position in the flora resources in this region and played a key role in the preservation of flora of the reserve. The herb species are the important life forms, and with the fodder and medicinal species accounted for a larger proportion.