[Objective] The configuration of ecological systematic measures of soil and water conservation for drought resistance in typical black soil region was discussed to provide theoretical support for the sustainable development of ecological agriculture in the region.[Methods] Under the principle of ecology, and method of water balance analysis was adopted, the drought relief system constructed by ecological measures of Baiquan County was built and evaluated. The county lied in an transition from semi-arid area to sub-humid area, where soil was seriously eroded.[Results] (1) The proportion of ecological drought relief measures that focus on soil and water conservation in the region was optimized. (2) Ecological measures for drought relief system eased off drought disaster. E.g., spring drought almost never happened from 2005 to 2009 in the region. In average, drought frequency decreased by 28.5% in comparison with that of adjacent counties in 10 years. (3) Water balance analysis showed that the regional water utilization ratio increased by 13.6%.[Conclusion] Ecological drought relief measures for soil and water conservation is an effective way of ecological construction for semi-arid sub-humid and soil loss region. It had obtained significant ecological, economic and social benefits in the case of systematic configuration of ecological measures for drought resistant in Baiquan county. The drought resistant measures should be configured according to local natural conditions and environmental characteristics.