[Objective] This study aims to quantitatively analyze the state of soil erosion in Guangxi Zhuang Autonomous Region, especially on the relationship between soil erosion and land uses and provides a basis for scientific control of soil erosion.[Methods] Based on RUSLE model, the modification factor M of karst rocky desertification was introduced to construct the soil erosion model suitable for Guangxi Zhuang Autonomous Region.[Results] ① In 2015, the soil erosion modulus of the region was 135.51 t/(km²·a). The soil erosion thickness was 0.08 (mm/a). The soil erosion area was 2.52×10⁴ km², and the soil loss was 3.21×10⁷ t, of which the soil erosion area of karst area was 1.86×10⁴ km², accounting for 73.81% of the soil erosion area and 31.01% of total soil loss. ② The percentage of soil loss from different land uses in total soil loss was:cultivated land(37.58%) > woodland(30.94%) > grassland(16.10%) > garden land(6.39%) > industrial and mining land(4.09%) > bare land(2.16%).[Conclusion] The land use changes induced by human interferences have greatly affected the spatial pattern of soil erosion in the whole area.