[Objective] In order to understand the non-point source pollution in Three Gorges Reservoir area of Hubei Province to find the main pollution sources and the key control area.[Methods] The non-point source pollutions of nitrogen and phosphorus emissions in 1990, 2000, 2005 and 2010 were calculated with the rainfall erosivity coefficient and simulated by river export coefficient model, the temporal and spatial distribution characteristics of nitrogen and phosphorus emissions of various pollution sources and their contribution rates were analyzed.[Results] TN emissions was more than 2 500 t and TP emissions was more than 250 t, and they both got the highest in 2000. The average annual TN emissions were 3 612.78 t/a and TP was 393.75 t/a, the annual TN and TP emission intensity were 3.10, 0.34 kg/(hm²·a). Therefore the study area was mainly nitrogen polluted. Paddy field and dry land were the main causes of nitrogen pollution source, the followed source was rural population. Paddy field and dry land were the main contributions of phosphorus pollution, pig breeding was the next one.[Conclusion] The non-point source pollution in the study area had its spatial distribution characterized by its low pollution in both sides and high in the middle part. Badong district was recognized as the key control area of nitrogen and phosphorus emissions.