[Objective] The advancement and practicality of wet-spraying vegetation-compatible concrete (VCC) were studied to provide a reference for ecological protection of engineering slopes.[Methods] The application of the new technology in the slope protection of a channel connected to Huama Lake in Ezhou City, Hubei Province, was presented. The effects of slope protection and soil and water conservation were observed. Furthermore, the plant coverage, plant density, average plant height, and species diversity index were tested on site.[Results] The technology could keep the slopes remained stable. The VCC substrate could adhere well to the slope surface, without forming gullies and slumps, with good soil and water conservation. The fundamental contradiction between the spraying of the VCC substrate and its adhesion to the slope surface was successfully solved. One month after the construction, the overall vegetation coverage of the slope reached more than 90%. The Shannon-Wiener diversity index, the Pielou evenness index, and the Simpson dominance index of the vegetation in the gentle-slope area were similar to those in the steep-slope area, but there were differences from the natural slope. The overall cost of the new technology (wet-spraying version) was 5%~15% lower than that of the old one (dry-spraying version).[Conclusion] As an upgraded version of dry-spraying VCC, this new technology shows significant advancements and can be used for ecological protection of engineering slopes.