[Objective] The health status and existing problems of the mountains-rivers-forests (grasslands)-farmlands-lakes-human life communities at Chongqing area in the Three Gorges reservoir (hereinafter called Chongqing reservoir area) were studied, and the interactions between the subsystems and humans was discussed in order to provide a reference for the ecological protection, green development, ecological civilization construction, and harmonious development of the reservoir area.[Methods] Twenty one counties (districts) of Chongqing City in the Three Gorges reservoir of the Yangtze River(abbreviated as “Chongqing reservior area”) were used as examples. For these, we constructed the health evaluation index system of life community from the perspective of mountains-rivers-forests (grasslands)-farmlands-lakes-human, and evaluated the health status of the communities. These were divided into four health types with the clustering analysis method based on the relevant geographic data using 3S technology and socioeconomic statistical data.[Results] ① As a whole, the ecological system for the mountains-rivers-forests (grasslands)-farmlands-lakes-human life community in Chongqing reservoir area was classified in the sub-health group. ② The features of the “mountain” subsystem reflected the vulnerability, instability, and low carrying capacity of the ecological environment in the Chongqing reservoir area. ③ The “human” subsystem showed that the development of the county's economy and society was lagging behind and there was an obvious conflict between socioeconomic development and ecological protection. ④ The structure and function of the “forest and grassland” subsystem need upgrading and optimizing.[Conclusion] In the future, the restoration and management of the lakeside systems of mountain forests (grasslands) should be focused on the forest (grassland), field, lake, and human subsystems, along with further strengthening of the basic and applied technological research in the area, in order to achieve more scientifically integrated governance, health management, and sustainable management for the mountains-rivers-forests (grasslands)-farmlands-lakes-human community system.