[Objective] The change characteristics of eco-environmental quality in the Shenfu-Dongsheng mining area during 1995—2020 were analyzed, in order to provide a scientific basis for improving the ecological environment of the region. [Methods] Principle component analysis was used to create the remote sensing ecological index (RSEI) based on dryness index (NDSI), greenness index (NDVI), heat index (LST), and humidity index (WET) obtained from Landsat 5 TM data and Landsat 8 OLI data (1995—2020). RSEI was divided into five grades by reclassification, and the center of gravity migration of RSEI grades Ⅰ—Ⅴ was analyzed according to the center of gravity migration method. The spatial change law of RSEI was analyzed in order to determine the dynamic monitoring and evaluation of eco-environmental quality of the Shenfu-Dongsheng mining area by using RSEI. [Results] ① The ecological environment of the Shenfu-Dongsheng mining area significantly improved from 1995 to 2020, and the area showing an upward trend accounted for 42.22% of the total area of the mining area. The greenness and dryness indicators had a greater impact on the eco-environmental quality of the mining area. ② Grassland and cultivated land were the main land use types of eco-environmental quality in the mining area, and the change in eco-environmental quality was greatly affected by the change of cultivated land and grassland area. ③ The eco-environmental quality of the mining area was based mainly on grades Ⅱ and Ⅲ. The migration ranges of grades Ⅰ, Ⅱ, and Ⅴ were relatively large, and the center of gravity migrated to the southwest and northwest of the mining area. [Conclusion] The eco-environmental quality of the Shenfu-Dongsheng mining area showed an overall upward trend from 1995 to 2020, and this trend was greatly affected by vegetation growth and human activities.