[Objective] The optimal combination of three environmental materials for soil aggregate structure and physicochemical properties improvements were examined, in order to solve the problems of poor soil structure and serious soil and water loss in the process of soil reclamation in the alpine region of Qinghai-Xizang region. [Methods] Using the Qinghai Delni Copper Mine as the research site and utilizing the local serpentine residue soil and raw soil, the effect of mixing three kinds of materials, namely binder, long fiber, and rice husk, on the soil improvement was investigated through the soil cultivation simulation orthogonal test, and the ratio of the mixed materials with the best effect was screened out. [Results] Orthogonal polar results showed that the binder had a stronger effect on soil aggregates, total porosity, field water holding capacity, and soil bulk density, whereas long fibers and rice husk had a stronger effect on pH value and total salt content. Binder incorporation increased soil bulk density but decreased soil pore space compared to the control (CK). Long fibers and rice husk significantly decreased soil pH value, increased total porosity and field water holding capacity, and suitably increased total salt content. The optimal combination for soil aggregates and pH value was A₂B₂C₃ (binder 0.074 g/kg, long fiber 2.960 g/kg, rice husk 11.110 g/kg). Soil bulk density, total porosity, and field water holding capacity regulation were optimized using the combination A₁B₂C₂ (binder 0.037 g/kg, long fiber 2.960 g/kg, rice husk 7.410 g/kg), and the optimal combination for total salt content was A₃B₁C₂ (binder 0.111 g/kg, long fiber 1.480 g/kg, rice husk 7.410 g/kg). [Conclusion] The optimal formula for soil matrix restoration in the alpine mining area was obtained as A_1.5B₂C₂, that is, binder 0.056 g/kg, long fiber 2.960 g/kg, and rice husk 7.410 g/kg as the optimal ratios, which could improve the soil structure and enhances the capacity of soil and water conservation in the alpine mining area of Qinghai-Xizang region.