A comprehensive index is used to analyze the regional disparity of soil erosion in Guangdong province. The result shows regional disparity of soil erosion is distinct in Guangdong province as a whole, and erosion in the northeast is greater than in the northwest. Natural erosion occurs mostly in granite mountainous hilly regions and the Pearl river delta hill along the seashore in Guangdong province. Human caused soil erosion is mainly in Pearl river delta region, where the economy is developing most actively. This includes Shenzhen, Zhuhai, Dongguan at the center and extends to eastern seashore, eastern mountains and western seashore gradually.