This paper mainly analyzes the natural and anthropogenic causes of grassland desertification in the Ruoergai Plateau using the method of remote sensing and field investigation.Results show that grassland desertification is due to the comprehensive influence of environment and human activities.Grassland desertification has become a serious eco-environmental problem in the Ruoergai Plateau,and therefore some controlling measures for grassland desertification in Ruoergai Plateau are presented.