Quantitatively study on land use change and ecosystem service value in fast developing areas will be a scientific basis for reasonable pricing,effective compensation of ecological resources,and coordinated development of natural ecosystem and socioeconomic system. Analysis of the changes of land use in Guangzhou City adopeted the single land use dynamic degree model,land use degree comprehensive index,and land use degree change rate. The coefficient of ecosystem service value proposed by Costanza and Xie Gaodi was used to Quantitatively study on land use ecosystem service value and its influence mechanism in Guangzhou City. The relationship between ecosystem service value and its major factors of social economy was explored by correlation analysis and sensitivity analysis. The results showed that total value of ecosystem service of land use in Guangzhou City decreases year by year，and ecosystem service values of forestland,water and garden land account for a higher percentage. The changes of land use structure and the area of different types of land cause a fluctuation in ecological service value. There is a negative correlation between ecosystem service value and population,GDP and urbanization degree，which indicates that the economy development is the cost of the loss of ecosystem service value. The change of ecosystem service value lacks elasticity with population,P and urbanization degree，comparatively speaking,it is sensitive with the population changes,then is urbanization degree，and with no sensitive with GDP.