The morp hological anatomy of stems and leaves of Artemisia sacrorum Ledeb. var . messerschmidtiana at 200 mg/ L of lead was studied. The changes were manifested as follows : For the stems of non-mining area eco-type at 200 mg/ L of lead, there were few changes in the organizational structure. The stems of mining area eco-type showed the adaptability to lead : both the thickness of epidermal and cell wall increased.The thickness of catheter of xylem increased and there was black substance in the catheter . For the leaves of non-mining area eco-type, there were great changes by lead stress. The entire structure of organization was loose; the shape of cell was irregular ; the sizes of cells were not the same ; some cells appeared disintegration in the organization ; and the chloroplast contained in the whole cells decreased significantly. But for t he leaves of mining area eco-type, the organization was completed ; the cells arranged closely ; the shapes of cells were regular ; and the sizes of cells were the same. Mining area eco-type appeared strong adaptability to lead st ress, which provides an excellent germplasm resource for the theory and practice of phytoremediation of lead contaminated soil .