Taking Dongguan City as the study area and applying satellite images of the Landsat TM/ETM+ in five different times,authors discussed characteristics of land use changes in the three aspects of the quantitative change,centric migration,and spatial differentiation of land uses and analyzed its driving factors from natural and human perspectives.Results from the study showed that(1) from 1988 to 2005,the overall land use change was the greatly decreased farmland and rapidly expanded urban land;(2) gravity centers of all the land uses moved far away and centric migration of farmlands was basically opposite to that of urban land;(3) spatial autocorrelation for farmlands was deceased and that for urban lands was enhanced;(4) economic development and population growth were the main driving factors for land use changes in the study area and land uses in the area with low altitude and gentle slope changed more rapidly because of topographical conditions.