Climate factors including precipitation and temperature have significant effects on agricultural pro-duction. Traditional statistics, EOF analysis and wavelet analysis were applied to analyze the characteristics of periodic variations and spatial distribution of precipitation and temperature in this region based on data col-lected at the 12 weather stations in Weihe River basin during 1957-2009. The results show that： (1) The precipitation and temperature in the basin is affected by larger scale weather systems. The abnormity of pre-cipitation and temperature in Weihe River basin were simultaneous, and the abnormity of precipitation and temperature differed between south and north, and in the east and west. (2) Morlet wavelet transform indi-cated that the major periods for precipitation was about 30 years or more, while the main periods for annual mean temperature and mean maximum temperature were about 29 years or more.