[Objective] To analyze the influence of different slope, soil bulk density, soil moisture content, and irrigation water amount on initial time of runoff during furrow irrigation erosion of cinnamon soil in Western Liaoning Province, in order to reduce the furrow irrigation erosion and guide the irrigation further. [Methods] The scouring experiment was conducted by orthogonal design. The method of response surface analysis with 4 factors and 3 levels was adopted to build a quadratic equation for initial time of runoff and soil erosion amount. [Results] The initial time of runoff was within 20.05 s and the smallest was 3.03 s. The determination coefficient of the quadratic equation was 0.998 9 and 0.999 2, respectively. [Conclusion] Slope, irrigation amount, soil bulk density and soil moisture content were negatively correlated with initial time of runoff, and had a significant effect on it. The influence order was as following: irrigation amount > slope > soil bulk density > soil moisture content. The quadratic equation build in the experiment was well fitted. Irrigation mode of minimal erosion amount under different slope was obtained by numerical calculation.