[Objective] To analyze the spatiotemporal evolution regulation of eco-efficiency of land utilization in order to put forward an optimization scheme on land utilization in Jilin Province. [Methods] The eco-efficiency of land utilization of the nine cities and areas in Jilin Province during 2002 to 2011 were evaluated based on the CCR-1 model of the data envelopment analysis(DEA). [Results] (1) In terms of DEA, the eco-efficiency of land utilization in Songyuan, Baicheng, Yanbian of Jilin Province are all effective, while the data in Changchun, Siping, Jilin, Liaoyuan, Tonghua and Baishan cities of Jilin Province were fluctuant. (2) The eco-efficiency of land utilization in the center area of Jilin Province is low while the efficiency in the east and west area is relatively high. [Conclusion] The emissions of ammonia nitrogen, COD, sulfur dioxide, waste water and dust are the main influencing factors related to the eco-efficiency of land utilization.