[Objective] The influence of brackish water drip irrigation on soil salt and alkali in Manasi River Basin was investigated in order to provide theoretical basis for the scientific utilization of brackish water and saline-alkali land management in arid areas of Xinjiang area. [Methods] The experiment was conducted in Manasi River Basin in Xinjiang area, and the influence of brackish water irrigation on soil salt movement regularity and soil pH value were analyzed under the condition of strong evapotranspiration. [Results] Drip irrigation reduced the salt in top layer(0-30 cm) soil, leading to soil salt cluster distribution at the bottom; periodical change of soil salt was significant with the variation coefficient ranging from 48.2% to 48.2%, therefore, the top layer soil(0-30 cm) have the risk of salt accumulation on the surface soil; pH value was negatively correlated with salt movement, soil pH value showed the trend of fluctuation rise after irrigation.[Conclusion] Plough layer soil salt reduced, while the risk of basicity(pH value) rise occurred at the same time.