[Objective] We aimed to study the effects of slope on soil pH value, carbon, nitrogen, phosphorus content in sandy land in order to reveal the variation of soil nutrients under different micro-topographical conditions, and provide a theoretical reference for environmental construction in sandy land. [Methods] The plots were selected from sandy land in Inner Mongolia grassland ecosystem research station(IMGERS). The effects of micro-topographical position on pH value, carbon, nitrogen and phosphorus content of soil were investigated. [Results] The pH values in different micro-topographical position showed as: sunny slope > slope base > shady slope > top of slope; The organic carbon content average showed as: slope base > shady slope > sunny slope > top of slope; The content of phosphorus showed as: slope base > shady slope > top of slope > sunny slope. Nitrogen content at the slope base and shady slope was higher than that at the top and sunny slope. [Conclusion] The variable coefficient of pH value, nitrogen, phosphorus content at top and sunny slope was higher than that at the base and shady slope. The variable coefficient of soil nutrient varied significantly among different micro-topographical positions.