[Objective] The spatial distribution of nutrients and pollution status of Tangpu reservoir were elucidated to provide relevant basis for water quality protection. [Methods] The contents of total organic carbon(TOC), total nitrogen(TN), ammonium-nitrogen(NH⁺₄-N), nitrate-nitrogen(NO₃-N), total phosphorus(TP) and available phosphorous were analyzed. Meanwhile, the sediment pollution status was assessed using organic nitrogen index (ON) and organic index(OI). [Results] The mean contents of TOC, TN and TP in the basin were 12.23 g/kg, 1.22 g/kg and 0.49 g/kg, respectively. In 0-20 cm layer of sediment, TN, TP and TOC concentrations are higher than those in other layers of sediment. With the increase of sediment depth, the content of pollutants decreased. The concentrations of pollutants are roughly constant below 40 cm. The organic index of the sediment is 0.13(level Ⅱ). [Conclusion] The pollution of sediment in Tangpu Reservoir is slight, but the content of nitrogen is high. Therefore, attention should be paid to the nitrogen pollution in the sediment.