[Objective] Organic carbon soil amendment was compounded to provide technical support for sustainable development of maize industry in Hexi irrigation area.[Methods] The study was conducted on the effect of organic carbon soil amendment on sandy soil in Ganzhou district, Zhangye City, Gansu Province through field experiment.[Results] The amount of soil organic carbon amendment was positively correlated with indices of porosity, aggregate, water holding capacity, organic matter, available nutrients, microbial biomass, enzyme activity and maize yield, while was negatively correlated with volume weight and pH value. After organic carbon amendment was applied, soil volume weight, pH value, Hg, Cd, Cr and Pb, were all decreased by 8.46%, 4.87%, 17.95%, 27.78%, 15.75% and 18.03% as compared with the effects of conventional fertilizer; indices of total porosity, aggregate, water holding capacity, organic matter, alkali-hydro nitrogen, available phosphorus and available potassium respectively increased by 8.15%, 23.98%, 8.15%, 3.16%, 0.10%, 2.13% and 1.18%; fungi, bacteria, actinomyces, sucrase, urease, phosphatase and corn fertilizing profits increased by 59.18%, 41.75%, 23.28%, 59.18%, 13.54%, 10.71% and 2, 180.40 yuan/hm², respectively.[Conclusion] The sandy soil physical and chemical properties and biological properties can be effectively improved by the application of organic carbon soil amendment, and the maize yield increased as well.