[Objective] The hazard assessment of debris flow was studied in order to provide an effective method for determining the weights of hazard assessment indexes in debris flow prone area.[Methods] In view of the weakness of single assigning weight method, analytic hierarchy process (AHP) and entropy method were adopted respectively to determine the subjective and objective weights of the debris flow hazard assessment indexes for the China-Pakistan highway, then the comprehensive weights were estimated based on combined weight method. Taking the debris flow along the China-Pakistan highway as a case study, this paper selected ten assessment indexes including magnitude, frequency, length of main groove, basin incision density, basin area, relative difference of elevation, longitudinal slope of main groove, maximum rainfall during 24 hours, thickness of loose deposit, length of mud and sand supply. The method mentioned above was used to assess the hazard of debris flow in this area after the acquisition of field data of debris flow. Besides, the results coincided with the set pair analysis method and field investigation results.[Results] Only five debris flow gullies, accounting for 25% of the total, were moderate dangerous, which meant that most debris flow gullies in this area were high dangerous.[Conclusion] The evaluation results were consistent with the field investigation, which confirmed the reliability of the method.