[Objective] A minimum cumulative resistance model was established to perform the function partition of landscape ecological safety pattern, and ecological source land was used to provide reference for the regional ecological environment protection.[Methods] The land use change data of Kaizhou District in Chongqing City in 1990, 2000 and 2010 were firstly adopted to analyze the distribution characteristics of land use types in terms of terrain gradient by using topographic index. Then, landscape pattern, elevation and slope were integrated to build a minimum cumulative resistance model.[Results] ① The topographic index ranges from 0.046 to 1.069 in Kaizhou District. The topographic index values of woodland and grassland are larger, and the topography index value of cultivated land is small; ② According to the minimum value of cumulative resistance and the partition principle of mutation point, the studied area was divided into four functional areas, termed as ecological conservation core area, ecological buffer area, ecological sensitive area, production and living area. During the period of 1990-2010, ecological conservation core area was small; ecological buffer area and ecological sensitive area did not change dramatically; production and living area became larger.[Conclusion] The topographic index is more advantageous for analyzing the spatial distribution characteristics of complex regional landscape with low altitude, elevation and slope combination.