[Objective] The spatial distribution characteristics of landslides in the Zhong County syncline in the Three Gorges Reservoir area were studied in order to provide theoretical basis for the prevention and control of geological disasters in this area.[Methods] On the basis of detailed field geological investigation, this paper took the Zhongxian County syncline in the Three Gorges Reservoir Area as the research focus and made in-depth discussions on the relationship between Zhongxian County syncline and landslide distribution characteristics by applying relevant theories of structural geology.[Results] The local structure of Zhongxian County syncline can be divided into three sections:the composite section by Northern Zhongxian County syncline and Wanxian County syncline, the main section of Central Zhongxian County syncline, and the composite section by southern Zhongxian County syncline and SN trending structure.[Conclusion] The landslide is mainly distributed in the northern and southern sections, and the landslide scale of the main section is relatively small. The spatial evolution characteristics of landslide in each section are different correspondingly as local structural features change.