[Objective] The discharge of acid mine drainage in metal mining area causes serious environmental pollution, and is difficult to control. This study designed and implemented the technology system of acid mine drainage control based on the combination of source controlling and terminal treatment, which provided a new solution for the treatment of acid mine drainage.[Methods] Based on the principle of "source control and terminal treatment", a comprehensive prevention and control technology system for acid mine drainage was established in Dabaoshan mining area of Guangdong Province.[Results] A cut-off drainage system was established to implement rainwater and sewage diversion, and to reduce the amount of acid mine drainage generated from the source. The storage capacity of the mud tank was 2.81×10⁶ m³. The new sewage treatment plant could process acid wastewater as much as 4.50×10⁴ t/d. The mine acid wastewater treatment system established in this study can achieve the goal of prevention and control in acidic wastewater during the rainy season.[Conclusion] Based on combined utilization of ditch (cutting ditch), canal (drainage), reservoir (blocking mud), and plant (sewage treatment plant), it is possible to achieve the goal of prevention and control in acidic wastewater under certain conditions. The technical system constructed in this study can be used for acid mine drainage treatment in similar mining areas.