[Objective] The temporal and spatial change characteristics and driving factors of land use/cover during 2000-2015 were analyzed to provide a scientific basis for the ecological environment construction and sustainable development of Nanchong City, Sichuan Province.[Methods] Based on Landsat images and QuickBird high-precision remote sensing data in 2000, 2010, and 2015, the direction and amplitude of land use/cover change and land use/cover condition index were calculated.[Results] ① Over the past 15 years, cultivated land and woodland have been the major land use/cover types in Nanchong City, accounting for approximately 80%; however, there were varying degrees of mutual conversion among land use/cover types. ② The area of woodland increased by 1 006.2 km², which was mainly converted from cultivated land and grassland, whereas the area of construction land increased by 965.4 km², which was mostly converted from water and cultivated land. The area of cultivated land, grassland, and waterbody were reduced by 1 549.8, 307.9, and 90.4 km², respectively. ③ Over the past 15 years, the change in the land use/cover condition index showed a good trend for the woodland and construction land (i.e., the condition index change rate of land use/cover was positive), whereas the cultivated land showed a slip trend (i.e., the condition index change rate of land use/cover was negative).[Conclusion] During the past 15 years, the land use/cover in Nanchong City has changed greatly. The major driving factors of land use/cover change in Nanchong City were topography, population, urbanization level, and returning farmland to forestry.