[Objective] The spatial pattern of soil nutrient content in cultivated land and its spatial correlation with environmental factors were studied, in order to provide a theoretical basis for regional cultivated land soil fertilization control and agricultural ecological environmental protection.[Methods] Taking the cultivated land in Zaoyang City of Hubei Province as the research object, five soil nutrient indicators including soil organic matter, total nitrogen, available potassium, slow-acting potassium and available phosphorus were selected, and 10 environmental factors including soil parent materials, soil types, soil pH value, Elevation (DEM), surface undulation, slope, vegetation coverage index (NDVI), average temperature, average precipitation, and land use types were collected to analyze the spatial distribution characteristics of each soil nutrient and the correlations between the spatial differentiation characteristics of each soil nutrients and environmental factors by using ordinary Kriging interpolation and information entropy principle.[Results] The spatial heterogeneity of soil slow-acting potassium in Zaoyang City was not obvious, and the content of the whole area was relatively high; the other four nutrients all showed different degrees of spatial heterogeneity. The results of information entropy showed that the spatial patterns of the five soil nutrient contents were strongly correlated with soil-forming parent materials, soil type and climate shadow, but the degree of correlation was different; the topographic factors had a strong spatial correlation with total nitrogen and organic matter contents, and soil pH value. The value had a strong correlation with soil available potassium, slow-acting potassium and available phosphorus.[Conclusion] The soil nutrient pattern in Zaoyang City is strongly affected by natural factors, but the correlation index K value is low, indicating that it is affected by the chemical reaction of soil water and nutrient loss caused by man-made fertilization, crop consumption and irrigation and drainage in the later period.