[Objective] The spatiotemporal changes in land use types in Pingtang, Huishui, and Luodian counties surrounding the FAST (five-hundred-meter aperture spherical radio telescope) were analyzed, and the relation between land use changes and the ecological environment was explored, in order to provide reference suggestions for the environmental protection and improvement of the ecological environment around the FAST.[Methods] Based on the TM remote sensing image data of 2000, 2005, 2010, 2013 and 2017, RS and GIS technology were used to interpret the remote sensing image data to obtain the productive-living-ecological space of Huishui County, Luodian County and Pingtang County of Guizhou Province surrounding FAST. With these land use data, the regional ecological environment quality index and its ecological contribution rate were calculated, and the evolution characteristics of land use function and the response status of regional ecological environment in the past 20 years were analyzed.[Results] ① The forest land around FAST occupied the largest proportion, but showed a decreasing trend. The land use area of productive-living-ecological space was as follows:ecological area> productive area> living area. The area of living and production land increased from 1 671.74, 12.84 km² to 1 674.07, 25.66 km², respectively, the ecological land area decreased from 6 610.55 km² to 6 590.86 km². ② The construction of the FAST project accelerated the transformation of land use types and promoted the mutual conversion of forest ecological land, grassland ecological land, agricultural production land, and water ecological land around FAST. Among them, forest ecological land had the largest transfer area, accounting for 46.14% of the transferred area. ③ The eco-environmental quality index around FAST dropped from 0.471 0 to 0.468 1, and the eco-environment showed a downward trend. The development around FAST promoted the conversion of land use with high ecological environment to land use with low ecological environment.[Conclusion] There is a coupling relation between the ecological environment and land use changes around FAST. The quality of the ecological environment shows a downward trend as the ecological land changes to production and living land. Improving the ecological land around FAST is beneficial to safe operation of FAST project.