[Objective] Spatial and temporal patterns of intensive urban land use in Guangdong Province were studied in order to promote sustainable and intensive land use to facilitate the goal of ecological civilization construction.[Methods] An index of intensive land use was determined by using the entropy method. Spatial and temporal patterns were then analyzed by kernel density estimation and spatial autocorrelation analysis.[Results] ① In terms of time series, based on the best natural breaking point method, the intensive land use level was divided into four levels:Ⅰ, Ⅱ, Ⅲ, and Ⅳ, respectively, indicating increasing levels of intensive land use during 2012-2019. A definite gap in the level of intensive land use among cities in Guangdong Province was observed, but the gap was narrowing. ② In the spatial aspect, the intensive land use level had the characteristics of agglomeration. The spatial agglomeration situation was respectively low-low, low-high, and high-high type regions. High value areas were mainly located in parts of the Pearl River delta, and low value areas were located in the north of Guangdong Province. ③ The level of intensive urban land use differed over time, but the level of intensive urban land use was improved. In space, the level of intensive urban land use had the characteristics of agglomeration and correlation.[Conclusion] Cities should develop in accordance with local conditions. The Pearl River delta region should continue to optimize its industrial structure, while the Western and Northern Guangdong regions should, with the help of government policies, strengthen inter-regional linkages in order to narrow regional gaps.