[Objective] The influences of the desertification reversal process on soil wind erosion in the Mu Us sandland were studied in order to provide a scientific reference for the prevention and control of wind erosion and for ecological reconstruction in this area. [Methods] A total of eight remote sensing images were selected from 1986 to 2021, and ENVI 5.3 and ArcGIS 10.7 were used as the platform to invert the desertification of land in different periods in the Mu Us sandland. A desertification difference index (DDI) was constructed for the study area in 2021, and land in the Mu Us sandland was classified as non-, light, moderate, severe, and very severe desertification according to the natural fracture method. According to the inversion results, we applied the method of space instead of time to collect soil samples of different desertification types. We tested the soil samples and analyzed them for soil wind erosion erodibility influencing factors, such as soil mechanical composition, soil organic matter content, soil crust factor, and vegetation factors. [Results] The overall desertification of the Mu Us sandland tended to decline from 1986 to 2021, and the desertified land area shrank from 47 877.81 km² in 1986 to 45 914.06 km² in 2021 (a reversal rate of 56.11 km²/a). Desertification could be divided into three periods:1986-2001 was the desertification development period that exhibited decreasing trends for soil clay, silt, and organic matter content, and increasing trends for soil sand content, soil crust factor, and vegetation factors; 2001-2011 was the period of significant desertification reversal; and 2011-2021 was the desertification stabilization period. During the reversal period, the percentage content of soil clay, silt, and organic matter showed an increasing trend, and the soil sand grain percentage content, soil crust factor, and vegetation factors showed a decreasing trend. The greater the degree of reversal, the faster the rate of change of the factors. As desertification degree weakened, the percentage content of soil clay, silt, and organic matter showed a linear increasing trend, with increasing rates of 1.55%, 7.08% and 1.98%, respectively. The values of soil sand grain percentage, crust factor, and vegetation factors showed a linear decreasing trend, with decreasing rates of 8.62%, 0.13% and 0.23%, respectively. [Conclusion] The reversal process of desertification in the Mu Us sandland caused soil structure to become finer, crusts to develop, vegetation to increase, and soil erosion resistance to increase, thereby significantly inhibiting wind erosion of soil.