[Objective] The impacts of land use on terrestrial ecosystems are important for current global change research. The impacts of land use change on fractional vegetation coverage (FVC) were analyzed scientificaly to improve coordinated development of the social economy and ecological environmental quality while balancing development of the regional economy, in order to provide a reference for government departments to use in protecting and restoring regional ecological management.[Methods] Hubei Province was selected as the research area. Landsat remote sensing images and land use remote sensing data from 2000 and 2020 were obtained, and methods such as spatial processing of remote sensing data, a pixel binary model, and a land use transfer matrix were used. The temporal and spatial changes in FVC, land use type changes, and their effects on FVC in Hubei Province were analyzed.[Results] ① From 2000 to 2020, the area of cultivated land, grassland, and unused land in Hubei Province decreased, the area of water and construction land increased, and the area of forest land remained basically unchanged. The land use area sizes followed the order of forest land > cultivated land > water area > construction land > grassland > unused land; ② The average FVC in Hubei Province increased by 6.50 %. The average FVC of forest land, cultivated land, grassland, and unused land increased, while the average FVC of construction land decreased. ③ FVC in Hubei Province showed an overall increasing trend. The areas with increased FVC were mainly concentrated in the west and southeast parts of Hubei Province. Some areas also experienced vegetation degradation, mainly concentrated in the central and southern parts of Hubei Province and some areas in Northern Xiangyang. ④ During the FVC transfer process resulting from changes in land use types, the transfer process between higher FVC and high FVC areas of cultivated land was the most intense. The FVC transfer amount in forest land accounted for 47.87 % of the total transfer amount, while the FVC transfer amount for grassland accounted for only a small proportion of the total transfer amount (3.40 %).[Conclusion] Land use changes in Hubei Province were great from 2000 to 2020, resulting in an overall increase in FVC over time.